Chemically imbalanced: when marketing masquerades as science

You can access this book review here.

My reflections on this Drug Science Podcast

The 5-HT hypothesis of depression: https://holeousia.com/2025/03/19/the-5-ht-hypothesis-of-depression-with-prof-philip-cowen-and-dr-sameer-jauhar/ This podcast was released by DRUG SCIENCE on 12 March 2025. The podcast can be listened to here. As a former NHS psychiatrist and also as somebody … Continue reading My reflections on this Drug Science Podcast

The 5-HT hypothesis of depression with Prof Philip Cowen and Dr Sameer Jauhar

This podcast was released by Drug Science on 12 March 2025. The podcast can be listened to here. What follows is a full transcription of this podcast. Drug Science Podcast: … Continue reading The 5-HT hypothesis of depression with Prof Philip Cowen and Dr Sameer Jauhar

The antidepressant controversy

This is one of the educational seminars to be held at the RCPsych International Congress in Edinburgh, in June of this year: Given that nearly 1 in 4 of the … Continue reading The antidepressant controversy

“Murky stuff”

On the 20 July 2022, the following systematic review was published in Molecular Psychiatry. The authors were Joanna Moncrieff, Ruth E. Cooper, Tom Stockmann, Simone Amendola, Michael P. Hengartner & … Continue reading “Murky stuff”

“What is it about antidepressants that upsets them so much . . . “

Edinburgh, 2010, and I was in the audience when Professor Ian C Reid began with this question: “What is it about antidepressants that upsets them so much . . . … Continue reading “What is it about antidepressants that upsets them so much . . . “

“Conservative prescribing”

This editorial, an opinion piece by Prof David Healy, was recently published in the BMJ. In this post I intend to explore the arguments made around whether “chemical imbalance” was … Continue reading “Conservative prescribing”

Reaching cells

BJPsych Editorial: Questioning the ‘neuroprotective’ hypothesis: Does drug treatment prevent brain damage in early psychosis or schizophrenia? By Joanna Moncrieff. Reaching Cells, reply by Dr Peter J. Gordon, 9 February … Continue reading Reaching cells