Déjà vu
The recent publication in JAMA Psychiatry: Incidence and Nature of Antidepressant Discontinuation Symptoms: A Systematic Review and Meta-Analysis made me feel that I had been here before. Once again, a … Continue reading Déjà vu
Tag: Glyn Lewis
Antidepressant withdrawal and relapse: easily mistaken
This Editorial can be openly accessed from the Journal of Psychotherapy and Psychosomatics. It begins: One of the commonest stories encountered in psychiatric practice is a patient reporting that their … Continue reading Antidepressant withdrawal and relapse: easily mistaken
ANTLER + REDUCE
The ANTLER study The REDUCE trial Over millennia, philosophers, alive and dead, have agreed that science, a priori, must be based on a position of neutrality. This quest is one … Continue reading ANTLER + REDUCE
The ANTLER trial
The Maudsley Deprescribing Guidelines state that tapering of the antidepressant Sertraline normally takes between 3 months and 2 years. However, in the ANTLER trial 70% people who had been taking … Continue reading The ANTLER trial
The antidepressant controversy
This is one of the educational seminars to be held at the RCPsych International Congress in Edinburgh, in June of this year: Given that nearly 1 in 4 of the … Continue reading The antidepressant controversy
Defensive
The programme for the 2023 International Congress of the Royal College of Psychiatrists struck me as being defensive. The Congress keynote lecture was given by Sir Robin Murray. Despite his … Continue reading Defensive
Moderate to severe depression: No evidence that CBT is less effective than antidepressants
In relation to informed consent for evidence based interventions for moderate to severe depression this finding has not had the attention that it should have.
Published letters on the ANTLER Trial
The following letters comment on The ANTLER Trial and were published in the New England Journal of Medicine in November 2021. The reply by the ANTLER Study team reveals that … Continue reading Published letters on the ANTLER Trial