My reflections on this Drug Science Podcast

The 5-HT hypothesis of depression: https://holeousia.com/2025/03/19/the-5-ht-hypothesis-of-depression-with-prof-philip-cowen-and-dr-sameer-jauhar/ This podcast was released by DRUG SCIENCE on 12 March 2025. The podcast can be listened to here. As a former NHS psychiatrist and also as somebody … Continue reading My reflections on this Drug Science Podcast

The 5-HT hypothesis of depression with Prof Philip Cowen and Dr Sameer Jauhar

This podcast was released by Drug Science on 12 March 2025. The podcast can be listened to here. What follows is a full transcription of this podcast. Drug Science Podcast: … Continue reading The 5-HT hypothesis of depression with Prof Philip Cowen and Dr Sameer Jauhar

Are neurotransmitters passé in psychiatry?

This is one of the educational seminars to be held at the RCPsych International Congress in Edinburgh, in June of this year: [spelling mistakes as per conference programme] Our family … Continue reading Are neurotransmitters passé in psychiatry?

“Promulgating therapeutic recommendations”

The following letter, written by Dr Philip Cowen and Dr Chris Thompson, was published in the BMJ in October 1994 [this, as it happens, being mid-way through the ‘Defeat Depression … Continue reading “Promulgating therapeutic recommendations”

“uncritical partisan narrative”

In a previous post I shared this paper: The declarations of interest were given as follows: I have written the following open letter to the lead author: Sent: 22 May … Continue reading “uncritical partisan narrative”

“Antidepressants, withdrawal and addiction: where are we now?”

This perspective has just been published in the Journal of Psychopharmacology. My brief response to one of the authors can be read here, alongside further details of the competing interests of … Continue reading “Antidepressants, withdrawal and addiction: where are we now?”

‘At least 500 million years of nervous system evolution’

The British Journal of Psychiatry has a series called “100 words”. The above was a submission by Professor Philip J. Cowen published in 2013: 500 million years reduced to 100 … Continue reading ‘At least 500 million years of nervous system evolution’

“Bipolarisation”

This is a BMJ response written by me on the 8th June 2011. Four years on and I remain just as concerned about the over-medicalisation of mood disturbance. None of my words take … Continue reading “Bipolarisation”