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By Hole Ousia Posted on February 11, 2024

Confronting the Pharmaceutical Shadow in Psychiatry

It was welcome to read this thoughtful and informed response by Professor Om Prakash. Alas, British psychiatry continues to be in denial about this issue, such that even the review … Continue reading Confronting the Pharmaceutical Shadow in Psychiatry

Categories: Antidepressant prescribing, British Medical Journal, History of medicine, Medical Education, Pharmaceutical industry and Medical Education, Psychiatry, SchizophreniaTags: 2023;383:p2730, A Prescription Error, A Sunshine Act for Scotland, a conflation between marketing and education, antidepressants, Antiquary, Assessing faculty financial relationships with industry, Attacks on antidepressants: signs of deep-seated stigma?, BAP relationship with Industry, BBC Panorama - Who's paying your doctor?, BMJ, BMJ Rapid response, BMJ Rapid Responses, British Association for Psychopharmacology, British Indian Psychiatric Association Annual Conference, British Psychiatry is heavily influenced by opinion leaders, British Psychiatry: Marketing as 'Education', chemical imbalance, Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder, Confronting the Pharmaceutical Shadow in Psychiatry, Conspiracy of consensus, Defeat Depression Campaign, Dr Sameer Jauhar, Ethical Imperatives and the Integrity of Mental Health Practice, Evidence b(i)ased medicine – selective reporting from studies sponsored by the pharmaceutical industry, expert reaction to largest review of antidepressants, February 2024, Fiona Godlee, Hole Ousia, Increased global integration in the brain after psilocybin therapy for depression, Industry-biased education, Industry-biased evidence, industry-biased psychiatry, Inquiry thrown into doubt over members' links with manufacturers, Key Information on the use of antidepressants, More people should get pills to beat depression, Myths about mood disorders, Narrative controller, Narrative Controllers, Om Prakash, Paid Opinion Leader, paid opinion leaders, paid opinion leaders are a blot on medicine’s integrity and we should make them a thing of the past, PE1493, PE1493 by Peter John Gordon on a Sunshine Act for Scotland. To close the petition, PE1651: Prescribed drug dependence and withdrawal, Peter Scott-Gordon, POL, Politicians experts and patient representatives call for the UK government to reverse the rate of antidepressant prescribing, Position Statement on antidepressants and depression, Prescribed drug dependence and withdrawal, Professor Andrea Cipriani, Professor Carmine Pariante, Professor Catherine Harmer, Professor David Baldwin, Professor David Nutt, Professor Guy Goodwin, Professor Om Prakash, Professor Stephen Lawrie, Professor Wendy Burn: "The influence of pharma on most psychiatrists in the UK is negligible", Psychopharmacology Committee meeting of the Royal College of Psychiatrists, Realistic Psychiatry, rebel antiquary, Reversing the rate of antidepressant prescribing, Royal College of Psychiatrists and the British Association for Psychopharmacology, Science Media Centre, Selling sickness: the pharmaceutical industry and disease mongering, Social maverick, SSRI, The Antiquary, The defeat depression campaign, The influence of paid opinion leaders on the prescribing of antidepressants in the UK, The Law of the Few, The Narrative Controllers, The Rebel Antiquary, Torbjörn Waerner, Transparency at the Top, Undisclosed financial conflicts of interest in DSM-5-TR: cross sectional analysis, Undue Pharmaceutical Influence on Psychiatric Practice., Whats the beef, Why psychiatry needs an honest dose of gentle medicine

By Hole Ousia Posted on January 4, 2024January 8, 2024

The influence of paid opinion leaders on the prescribing of antidepressants in the UK

I submitted two rapid responses to the BMJ in relation to this published letter: Reversing the rate of antidepressant prescribing: I divided my responses in two so that the word … Continue reading The influence of paid opinion leaders on the prescribing of antidepressants in the UK

Categories: Antidepressant prescribing, British Medical Journal, Depression, History of medicine, Medical Education, Medical writings, NHS Hospitality Registers, NHS Scotland, Pharmaceutical industry and Medical Education, Psychiatry, Sunshine Act for ScotlandTags: 2023;383:p2730, A Prescription Error, A Sunshine Act for Scotland, a conflation between marketing and education, antidepressants, Antiquary, Attacks on antidepressants: signs of deep-seated stigma?, BAP relationship with Industry, BBC Panorama - Who's paying your doctor?, BMJ, BMJ Rapid Responses, British Association for Psychopharmacology, British Indian Psychiatric Association Annual Conference, British Psychiatry is heavily influenced by opinion leaders, British Psychiatry: Marketing as 'Education', chemical imbalance, Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder, Defeat Depression Campaign, Dr Sameer Jauhar, expert reaction to largest review of antidepressants, Fiona Godlee, Hole Ousia, Increased global integration in the brain after psilocybin therapy for depression, Industry-biased education, Industry-biased evidence, industry-biased psychiatry, Inquiry thrown into doubt over members' links with manufacturers, Key Information on the use of antidepressants, More people should get pills to beat depression, Myths about mood disorders, Narrative controller, Narrative Controllers, Paid Opinion Leader, paid opinion leaders, paid opinion leaders are a blot on medicine’s integrity and we should make them a thing of the past, PE1493, PE1493 by Peter John Gordon on a Sunshine Act for Scotland. To close the petition, PE1651: Prescribed drug dependence and withdrawal, Peter Scott-Gordon, POL, Politicians experts and patient representatives call for the UK government to reverse the rate of antidepressant prescribing, Position Statement on antidepressants and depression, Prescribed drug dependence and withdrawal, Professor Andrea Cipriani, Professor Carmine Pariante, Professor Catherine Harmer, Professor David Baldwin, Professor David Nutt, Professor Guy Goodwin, Professor Stephen Lawrie, Psychopharmacology Committee meeting of the Royal College of Psychiatrists, Realistic Psychiatry, rebel antiquary, Reversing the rate of antidepressant prescribing, Royal College of Psychiatrists and the British Association for Psychopharmacology, Science Media Centre, Social maverick, SSRI, The Antiquary, The defeat depression campaign, The influence of paid opinion leaders on the prescribing of antidepressants in the UK, The Law of the Few, The Narrative Controllers, The Rebel Antiquary, Torbjörn Waerner, Transparency at the Top, Whats the beef

By Hole Ousia Posted on December 6, 2023

Anti-amyloid drugs: Key questions

As published here.

Categories: Alzheimer's disease, Dementia, History of medicine, Medical Education, Medical writings, Neuro-imaging, Neuro-protection, NHS Scotland, Pharmaceutical industry and Medical Education, ScreeningTags: 'The Edinburgh Consensus: Preparing for the advent of disease-modifying therapies for Alzheimer's disease' Alzheimer's research & therapy, 11 May 2023 - Donanemab - Eli Lilly, 17 July 2023, 2023;382:p1852, 21 May 2023, 385;7, a blot a stain or perhaps something worse, a drug that is not effective cannot be cost-effective, A Sunshine Act for Scotland, ABPI, Accelerated approval of anti-amyloid drugs, accelerated approval pathway, Aducanumab and Donanemab for Early Alzheimer Disease: Estimating the true value, Adverts for 'Scottish Brain Sciences', Alberto J Espay, Alette M Wessels, Alzheimer, Alzheimer Scotland, Alzheimer Scotland: Annual Conference 2023, Alzheimer Society, Alzheimer's, Alzheimer's disease, Alzheimer's Drug Trial, Alzheimer's Drug Trial: What promising results means for treatments, Alzheimer's Society, Amar H kelkar, amylod, amyloid cascade, AMYVID, Association of the British Pharmaceutical Industry, August 2021, ‘Evidence Based Medicine’ or ‘Industry Biased Medicine’, ‘Looking to a brighter future’ – how today’s research, Baroness Cumberlege, BBC, Big Pharma, Blazing trails or the road to nowhere?, bleeding, bleeding and seizures, BMJ, BMJ 2008;336:1402, BMJ 2018;360:k135, BMJ 2023;382:p1659, brain swelling, Brain volume loss due to Donanemab, Caroline Wilson, CEO and Founder of Scottish Brain Sciences, Chief Executive of Alzheimer’s Research UK, competing interests, cost-effectiveness of Aducanumab and Donanemab, Craig Ritchie, Cumberlege Review, Dawn A Brooks, Dawn Brooks, declaration, declarations, Declarations of Interest, definitions, Dementia, Dementia expert Professor Craig Ritchie quits NHS job, Dementia's Medical-Industrial-Charity Complex, Disclosure UK, disease modification, disease mongering, disease-modifying, Donanemab, Donanemab in Early Symptomatic Alzheimer Disease, Donanemab leads to modest slowing of Alzheimer’s progression, Donanemab: bleeding and seizures, Donanemab:'The results may be misleading', Dr Alan Duncan, Dr Margaret McCartney, Dr Peter Gordon, Dr Peter J Gordon, early Alzheimer's disease, early diagnosis, early diagnosis is everywhere, early diagnosis of dementia, Edinburgh, Edinburgh Consensus, Edward R Scheffer Cliff, Eli Lilly, EPAD, Eric L Ross, Estimating the true value: Aducanumab and Donanemab for Early Alzheimer Disease, European Journal of Neurology, Expert reaction to approval of ADUCANUMAB, Express, FDA, first do no harm, fully informed consent, Gareth Iacobucci, General Medical Council, Glasgow Declaration, GMC, Good Medical Practice, headlines, Henry Simmons, Here’s a game: try and find a doctor’s conflicts of interest., Hide and Seek, Hiding and seeking doctors’ conflicts of interest, Hilary Evans, Hole Ousia, https://www.alzscot.org/conference23, immunoglobulin G1, independent experts or drug representatives in disguise, informed consent, infusion, Issues not considered in the 'Edinburgh Consensus', Jill Manthorpe, John R Sims, Key Opinion Leaders, Key opinion leaders and Industry, Key questions for the evaluation of anti-amyloid immunotherapies for Alzheimer’s disease, Keynote Lecture, learning and developments are offering hope for tomorrow, Marc Aurel Busche, Marc S Weinberg, Maree Todd, Mark A Mintun, MCI, Medical-Industrial-Charity Complex, Melbourne Dementia Research Centre, MHRA, mild cognitive impairment, Mintun et al, Mirror, monoclonal antibody, Monopoly, MSP, Narrative Controllers, Nature, New treatments for Alzheimer's disease, New York Times, newspaper reports, NICE guidelines, No Holds barred, No sunshine for Scotland, oining the world's first Brain Health Community, paid opinion leaders, paid opinion leaders are a blot on medicine’s integrity and we should make them a thing of the past, PE1493, pharma, Pharmaceutical Industry, Phase 3, placebo-controlled trial of Donanemab, PMCPA, preclinical Alzheimers, preclinical dementia, Prescription Medicines Code of Practice Authority, prevention, primum non nocere, prodromal dementia, Prof Ritchie said: "“We understand the disease, Prof Rob Howard, Prof Robert Howard, Professor Craig Ritchie, Professor Rob Howard, Professor Robert Howard, public health, radio 4, Ray Moynihan, RCPsych, RCT, Realistic Medicine, rebel antiquary, Registers of Interest, regulatory approval, research, Royal College of Psychiatrists, Sara Reardon, scanners, Science Media Centre, Scott Aytoun, Scottish Brain Sciences, Sebastian Walsh, seizures, side effects, Sky News, Snakes and ladders, snakes ladders and Monopoly, Soeren Mattke, Steve Illiffe, Steven E Arnold, study finds, Sunshine Act for Scotland, Sunshine legislation, t's boom time in industry, tau, The Edinburgh Consensus, the evidence of benefit probably does not outweigh the negatives, The Guardian, The hyperbole in the media and scientific response is unjustified and cruel to patients, The Narrative Controllers, The New England Journal of Medicine, The Rebel Antiquary, The report of the Independent Medicines and Medical Devices Safety Review, The World Tonight, timely diagnosis, timely diagnosis of dementia, Tom Russ, Too much Medicine, trailblazer, TRAILBLAZER-ALZ 2, Transparency, treatments for Alzheimer's disease, University of Cincinnati, US Food and Drug Administration, Vol 617, we understand what is is going on in the brain", worldwide trailblazing headlines of the latest anti-amyloid drug

By Hole Ousia Posted on December 6, 2023

Accelerated approval of anti-amyloid drugs

I fully share the concerns expressed by Professor Robert Howard:

Categories: Alzheimer's disease, Dementia, History of medicine, Medical Education, Medical writings, Neuro-imaging, Neuro-protection, ScreeningTags: 'The Edinburgh Consensus: Preparing for the advent of disease-modifying therapies for Alzheimer's disease' Alzheimer's research & therapy, 11 May 2023 - Donanemab - Eli Lilly, 17 July 2023, 2023;382:p1852, 21 May 2023, 385;7, a blot a stain or perhaps something worse, a drug that is not effective cannot be cost-effective, A Sunshine Act for Scotland, ABPI, Accelerated approval of anti-amyloid drugs, accelerated approval pathway, Aducanumab and Donanemab for Early Alzheimer Disease: Estimating the true value, Adverts for 'Scottish Brain Sciences', Alberto J Espay, Alette M Wessels, Alzheimer, Alzheimer Scotland, Alzheimer Scotland: Annual Conference 2023, Alzheimer Society, Alzheimer's, Alzheimer's disease, Alzheimer's Drug Trial, Alzheimer's Drug Trial: What promising results means for treatments, Alzheimer's Society, Amar H kelkar, amylod, amyloid cascade, AMYVID, Association of the British Pharmaceutical Industry, August 2021, ‘Evidence Based Medicine’ or ‘Industry Biased Medicine’, ‘Looking to a brighter future’ – how today’s research, Baroness Cumberlege, BBC, Big Pharma, Blazing trails or the road to nowhere?, bleeding, bleeding and seizures, BMJ, BMJ 2008;336:1402, BMJ 2018;360:k135, BMJ 2023;382:p1659, brain swelling, Brain volume loss due to Donanemab, Caroline Wilson, CEO and Founder of Scottish Brain Sciences, Chief Executive of Alzheimer’s Research UK, competing interests, cost-effectiveness of Aducanumab and Donanemab, Craig Ritchie, Cumberlege Review, Dawn A Brooks, Dawn Brooks, declaration, declarations, Declarations of Interest, definitions, Dementia, Dementia expert Professor Craig Ritchie quits NHS job, Dementia's Medical-Industrial-Charity Complex, Disclosure UK, disease modification, disease mongering, disease-modifying, Donanemab, Donanemab in Early Symptomatic Alzheimer Disease, Donanemab leads to modest slowing of Alzheimer’s progression, Donanemab: bleeding and seizures, Donanemab:'The results may be misleading', Dr Alan Duncan, Dr Margaret McCartney, Dr Peter Gordon, Dr Peter J Gordon, early Alzheimer's disease, early diagnosis, early diagnosis is everywhere, early diagnosis of dementia, Edinburgh, Edinburgh Consensus, Edward R Scheffer Cliff, Eli Lilly, EPAD, Eric L Ross, Estimating the true value: Aducanumab and Donanemab for Early Alzheimer Disease, European Journal of Neurology, Expert reaction to approval of ADUCANUMAB, Express, FDA, first do no harm, fully informed consent, Gareth Iacobucci, General Medical Council, Glasgow Declaration, GMC, Good Medical Practice, headlines, Henry Simmons, Here’s a game: try and find a doctor’s conflicts of interest., Hide and Seek, Hiding and seeking doctors’ conflicts of interest, Hilary Evans, Hole Ousia, https://www.alzscot.org/conference23, immunoglobulin G1, independent experts or drug representatives in disguise, informed consent, infusion, Issues not considered in the 'Edinburgh Consensus', Jill Manthorpe, John R Sims, Key Opinion Leaders, Key opinion leaders and Industry, Keynote Lecture, learning and developments are offering hope for tomorrow, Marc Aurel Busche, Marc S Weinberg, Maree Todd, Mark A Mintun, MCI, Medical-Industrial-Charity Complex, Melbourne Dementia Research Centre, MHRA, mild cognitive impairment, Mintun et al, Mirror, monoclonal antibody, Monopoly, MSP, Narrative Controllers, Nature, New treatments for Alzheimer's disease, New York Times, newspaper reports, NICE guidelines, No Holds barred, No sunshine for Scotland, oining the world's first Brain Health Community, paid opinion leaders, paid opinion leaders are a blot on medicine’s integrity and we should make them a thing of the past, PE1493, pharma, Pharmaceutical Industry, Phase 3, placebo-controlled trial of Donanemab, PMCPA, preclinical Alzheimers, preclinical dementia, Prescription Medicines Code of Practice Authority, prevention, primum non nocere, prodromal dementia, Prof Ritchie said: "“We understand the disease, Prof Rob Howard, Prof Robert Howard, Professor Craig Ritchie, Professor Rob Howard, Professor Robert Howard, public health, radio 4, Ray Moynihan, RCPsych, RCT, Realistic Medicine, rebel antiquary, Registers of Interest, regulatory approval, research, Royal College of Psychiatrists, Sara Reardon, scanners, Science Media Centre, Scott Aytoun, Scottish Brain Sciences, Sebastian Walsh, seizures, side effects, Sky News, Snakes and ladders, snakes ladders and Monopoly, Soeren Mattke, Steve Illiffe, Steven E Arnold, study finds, Sunshine Act for Scotland, Sunshine legislation, t's boom time in industry, tau, The Edinburgh Consensus, the evidence of benefit probably does not outweigh the negatives, The Guardian, The hyperbole in the media and scientific response is unjustified and cruel to patients, The Narrative Controllers, The New England Journal of Medicine, The Rebel Antiquary, The report of the Independent Medicines and Medical Devices Safety Review, The World Tonight, timely diagnosis, timely diagnosis of dementia, Tom Russ, Too much Medicine, trailblazer, TRAILBLAZER-ALZ 2, Transparency, treatments for Alzheimer's disease, University of Cincinnati, US Food and Drug Administration, Vol 617, we understand what is is going on in the brain", worldwide trailblazing headlines of the latest anti-amyloid drug

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