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Paradigms, pathologies and shifts

B0003857 Alzheimers' disease - plaque in the brain Credit: Med. Mic. Sciences Cardiff Uni. Wellcome Images images@wellcome.ac.uk http://images.wellcome.ac.uk Confocal image of an Alzheimer's brain showing a region of amyloid plaque. Confocal micrograph Published: - Copyrighted work available under Creative Commons by-nc-nd 2.0 UK, see http://images.wellcome.ac.uk/indexplus/page/Prices.html

The following extracts are taken from this perspective published in the Scotsman, 11 January 2018:

Pfizer has seemingly concluded that Alzheimer’s disease is far more complex than we had ever anticipated.

Perhaps this indicates that the 110 year old “paradigmatic pathology” of Alzheimer’s disease does itself need a paradigm shift.

Meantime, the “Edinburgh Consensus” demonstrates limitless faith in the current paradigm, to the extent that they recommend that research criteria should be introduced into the NHS.

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